Microfluidic systems that move and mix tiny amounts of liquids are used in laboratories for biotechnology, chemistry, and even the development of inkjet technology. Frequently, microfluidic devices are integrated into a single "lab on a chip" but fabricating such systems can be costly and time-consuming. Now, MIT researchers are using customized LEGO bricks to make a modular microfluidics platform. Their prototype system "could be used to manipulate biological fluids and perform tasks such as sorting cells, filtering fluids, and encapsulating molecules in individual droplets." From MIT:
To demonstrate modularity, (mechanical engineering grad student Crystal) Owens built a prototype onto a standard LEGO baseplate consisting of several bricks, each designed to perform a different operation as fluid is pumped through. In addition to making the fluid mixer and droplet generator, she also outfitted a LEGO brick with a light sensor, precisely positioning the sensor to measure light as fluid passed through a channel at the same location.
Owens says the hardest part of the project was figuring out how to connect the bricks together, without fluid leaking out. While LEGO bricks are designed to snap securely in place, there is nevertheless a small gap between bricks, measuring between 100 and 500 microns. To seal this gap, Owens fabricated a small O-ring around each inlet and outlet in a brick.
“The O-ring fits into a small circle milled into the brick surface. It’s designed to stick out a certain amount, so when another brick is placed beside it, it compresses and creates a reliable fluid seal between the bricks. This works simply by placing one brick next to another,” Owens says. “My goal was to make it straightforward to use.”
Here’s an interesting experiment: Using mouse-movement as a lie-detection technique. Cognitive psychologists and neuroscientists have long noted a big “tell” in human behavior: Crafting a lie takes more mental work than telling the truth. So one way to spot lies is to check someone’s reaction time. If they’re telling a lie, they’ll respond fractionally more […]
For €105, the delightful and enchanting silver Neuron Necklace is yours. Its just one of a number of clever items offered by science-inspired jewelry, which include brains, fetuses, spines and thyroid hormones. [Thanks, Heather!]
For more than a century there have been reports of a strange sea “monster” living in Loch Ness yet hard evidence is, er, lacking. Now, evolutionary biologist Neil Gemmell of the University of Otago is hoping that DNA testing could perhaps shed some light on what people claim is Nessie. For two weeks, Gemmell and […]
Businesses big and small use Microsoft Excel for everything from data visualization to bookkeeping, and chances are you’ve already had some exposure to this ubiquitous tool. Whether you’re looking to improve your hiring potential or boost your Excel efficiency, the Ultimate All-Level Excel Bootcamp can get you Excel-savvy with nearly 70 hours of training, and it’s […]
The workday is long, and inevitably, you’re going to find yourself needing to take a break from the daily grind. With Mini Materials Miniature Cinder Blocks, you can take some time for yourself and decompress by turning your desk into a miniature construction site. They’re available today in the Boing Boing Store for $22.49. Handmade […]
Handheld radios might seem a bit archaic, but in an emergency situation, few things will keep you as reliably connected to the outside world. This Emergency Multi-Function Radio & Flashlight takes the utility of the tried-and-true radio and combines it with a powerful flashlight and self-sufficient energy system. It’s available in the Boing Boing Store for […]