Scientists combined multiple imaging technologies to deliver an unprecedented 3D view inside the body of crawling cancer cells, spinal cord circuit development, and immune cells traveling within a zebrafish (above). Nobel laureate Eric Betzig and his colleagues at the Howard Hughes Medical Institute integrate a technology called lattice light sheet microscopy with adaptive optics resulting in a very expensive, 10-foot-long microscope. From HHMI:
“It’s a bit of a Frankenstein’s monster right now,” says Betzig, who is moving to the University of California, Berkeley, in the fall. His team is working on a next-generation version that should fit on a small desk at a cost within the reach of individual labs. The first such instrument will go to Janelia’s Advanced Imaging Center, where scientists from around the world can apply to use it. Plans that scientists can use to create their own microscopes will also be made freely available. Ultimately, Betzig hopes that the adaptive optical version of the lattice microscope will be commercialized, as was the base lattice instrument before it. That could bring adaptive optics into the mainstream.
“If you really want to understand the cell in vivo, and image it with the quality possible in vitro, this is the price of admission,” he says.
More videos here.
YouTuber Retic over at Prehistoric Pets TV has a huge collection of pythons and other ancient creatures. Here he shows how and why a clutch of python eggs can be lifted up in giant sticky clumps.
If you’ve been using or abusing an opioid, then your pee’s been full of opioids. When your opioid-laced pee gets flushed away, those opioids wind up in our water: our reservoirs, streams and oceans. And that, friends, is why mussels are failing drug tests. According to CBS News, scientists at Washington’s Department of Fish & […]
Transgender model and activist Munroe Bergdorf hosts the new Channel 4 documentary What Makes a Woman? Science and society are grappling with the complex and contentious topics of sex, sexuality, and gender. New research and evidence demonstrate that simplistic binaries are more complicated than previously believed.
Businesses big and small use Microsoft Excel for everything from data visualization to bookkeeping, and chances are you’ve already had some exposure to this ubiquitous tool. Whether you’re looking to improve your hiring potential or boost your Excel efficiency, the Ultimate All-Level Excel Bootcamp can get you Excel-savvy with nearly 70 hours of training, and it’s […]
The workday is long, and inevitably, you’re going to find yourself needing to take a break from the daily grind. With Mini Materials Miniature Cinder Blocks, you can take some time for yourself and decompress by turning your desk into a miniature construction site. They’re available today in the Boing Boing Store for $22.49. Handmade […]
Handheld radios might seem a bit archaic, but in an emergency situation, few things will keep you as reliably connected to the outside world. This Emergency Multi-Function Radio & Flashlight takes the utility of the tried-and-true radio and combines it with a powerful flashlight and self-sufficient energy system. It’s available in the Boing Boing Store for […]