This spoof on the confusing CDC guidelines just had to be

Q-injected anti-vaxxers lead to an ever-changing (and never-ending) Covid virus, and the combination of the two leads to ever-changing CDC guidelines that can sometimes look as confusing as a stacked pole of parking signs on a Los Angeles boulevard.

For example, this is just one of many, many similar (yet different, so pay attention!) paragraphs from the CDC's guidelines:

Do not travel during your 5-day quarantine period. Get tested at least 5 days after your last close contact and make sure your test result is negative and you remain without symptoms before traveling. If you don't get tested, delay travel until 10 days after your last close contact with a person with COVID-19. If you must travel before the 10 days are completed, wear a well-fitting mask when you are around others for the entire duration of travel during the 10 days. If you are unable to wear a mask, you should not travel during the 10 days.

So of course comedian Desi Lydic of The Daily Show couldn't pass up an opportunity: