When done by medical professions, under very specific circumstances, a fecal transplant can mean the difference between life and death: implanting feces containing healthy gut microbiome into a patient's body has been used by doctors as a way to help fight antibiotic-resistant super bugs, like Clostridium difficile. — Read the rest
Biohacker Josiah Zayner suffered from persistent digestive problems so he decided to undertake an extreme self-experiment: He isolated himself in a hotel room, took massive doses of antibiotics, and then gave himself a fecal transplant to transform his own microbiome. Mark Frauenfelder and I interviewed Josiah about biohacking, cheap genetic engineering kits, and, of course, his own full body microbiome transplant in this episode of For Future Reference, a new podcast from Institute for the Future:
British science writer Ed Yong's new book I Contain Multitudes: The Microbes Within Us and a Grander View of Life is a history of gut flora and bacteria, which first entered our consciousness as a scourge to be eliminated and has lately become something between a cure-all (see the universe of "probiotic" food supplements) and a superfood (think of the fecal transplants that have shown such promise in treating a variety of debilitating and dangerous health conditions).
By digging into the data on fecal transplants—which are highly effective at treating dogged gut infections, such as Clostridium difficile, in humans—Conrad realized that treatment didn't have to be that rough.
A woman whose c.difficile infection was treated with a fecal transplant from her overweight daughter experienced rapid and dramatic weight gain as soon as her daughter's microbial nation took hold in her gut.
University of Guelph researcher Emma Allen-Vercoe and her team have devised a method for creating artificial poop for use in fecal transplants, a promising therapy for people whose intestinal flora have been damaged by illness, antibiotics, or other therapies. The recipe involves a combination of indigestible cellulose and a starter culture of fecal bacteria. — Read the rest
Marie Myung-Ok-Lee in the New York Times: "I delivered my first donation, in Tupperware, and Gene took it into the privacy of his bathroom. I stayed, just in case I was needed, and after about half an hour, he came out and told me, with a look of wonder, that he was feeling better already. — Read the rest
Over the past few years, we've linked to a couple of stories about fecal transplants—a real medical procedure where doctors take a donor stool sample, dilute it, and inject it into the colon of a patient. It sounds gross. But it appears to be incredibly effective at treating certain intestinal issues. — Read the rest