Bacteria shown to have built immunity to hand sanitizers

Good news everyone: those superbugs we’re all so afraid of? They’re evolving to be immune to a number of those popular alcohol-based hand sanitizers we all assumed would help to keep us from getting sick. Nature’s amazing!

Seriously though, the planet is totally trying to kill us for all the shit we do to it.

From Ars Technica:

Bacteria gathered from two hospitals in Australia between 1997 and 2015 appeared to gradually get better at surviving the alcohol used in hand sanitizers, researchers found. The bacteria’s boost in booze tolerance seemed in step with the hospitals’ gradually increasing use of alcohol-based sanitizers within that same time period—an increase aimed at improving sanitation and thwarting the spread of those very bacteria. Yet the germ surveillance data as well as a series of experiments the researchers conducted in mice suggest that the effort might be backfiring and that the hooch hygiene may actually be encouraging the spread of drug-resistant pathogens.

The more the bacteria drink, the higher their resistance to alcohol becomes. They’re just like us!

The bacteria that researchers are most concerned about becoming tolerant to current booze-based sanitation products is called enterococcus faecium: it’s responsible for the majority of infections that folks pick up in a hospital environment and has already proven to be resistant to a number of antibiotics. According to this report, bacterial tolerance to alcohol-based sanitizers could undermine the way that hospitals prevent the spread of bacteria and other ugly stuff, on a world-wide basis.

Happy Hump Day. Read the rest

Bread can be made from a gangrenous wound's bacteria

Atlas Obscura just added an interesting new section on strange and wondrous foods, like salt-rising bread leavened with bacteria that cause gas gangene. Read the rest

3D printing bacteria to clean up toxic chemicals or make band-aids that heal

ETH Zurich researchers developed a "living ink" for 3D printers that's made from bacteria, nutrients, and a polymer gel. In a small scale demonstration, they printed a small 3D lattice of the material that cleaned up a beaker of contaminated water. From Science News:

Lattices packing various types of chemical-hungry bacteria could create special water filters or help clean up oil spills. And unlike free-floating bacteria, cells locked in a 3-D grid could be plucked out of cleaned-up water and reused somewhere else....

Bacteria-filled 3-D prints could also produce bacterial cellulose — a gelatinous substance used for dressing wounds. Bacterial cellulose is typically grown in sheets, but “imagine if you have a burn on your elbow,” (materials scientist Manuel) Schaffner says. “You try to wrap flat, wet tissue around this area, it’s prone to detach.” Swathes of cellulose grown on 3-D printed structures could precisely match the contours of specific body parts, curbing the risk of contaminants getting trapped under wrinkles in the cellulose or the material peeling off.

Read the rest

As bacteria build fortresses, scientists seek weak points for attacks

Bacteria are extremely adept at building biofilm cities, often in places humans don't want them: catheters, sewer lines, and our teeth, to name a few. Now scientists are working to unlock the structural mysteries in order to eradicate unwanted bacterial buildup. Read the rest

Scientists discover bacteria that eats waste plastic

Japanese researchers discovered a bacterium that eats polyethylene terephthalate (PET), the stuff used to make plenty of single-use plastic products that sit in landfills. The bacterium, named Ideonella sakaiensis, uses enzymes to break down the plastic into carbon and energy sources for the microbe. From Chemical & Engineering News:

To find microbes that could pull PET apart, a team led by Kohei Oda of Kyoto Institute of Technology and Kenji Miyamoto of Keio University screened 250 sediment, soil, wastewater, and activated sludge samples from a PET bottle recycling facility in Sakai, Japan....

The study’s first author, Shosuke Yoshida of Keio University, says that a PET pretreatment that would enlarge the polymer’s amorphous areas would make waste more appetizing for the bacterium. Also, he notes, it might be possible to engineer the enzymes to make them faster and more practical.

Bacteria Devour Polluting Plastic in Landfills (via SciAm)

A bacterium that degrades and assimilates poly(ethylene terephthalate) (Science) Read the rest

Watching the climate-cholera connection from orbit

Dr. Kiki Sanford on how scientists are predicting outbreaks from an unusual new vantage point.

NYT jumps on our smelly old 'I don't use soap' bandwagon

Sean Bonner writing for Boing Boing, 2011: "I haven't used soap or shampoo in a year, and it's awesome: a personal experiment." NYT, 2014: "My No-Soap, No-Shampoo, Bacteria-Rich Hygiene Experiment." Read the rest

Life is hard in Antarctica

Antarctica's Organic Lake is 8 degrees Fahrenheit, but the water doesn't freeze, thanks to a heavy concentration of salt. But wait, it gets more awesome. Despite the cold and the salt, Organic Lake is also home to a diverse array of life. Read the rest

Microbes and health: The debate continues

Last week, I linked you to a piece pointing out that three New York Times op-ed pieces linking bacterial exposure (or lack thereof) to autism, celiac disease, and allergies were all written by the same guy, Moises Velasquez-Manoff. His ideas are interesting, but there's also good reason to be skeptical. If you want to get a better idea of the arguments for and against Velasquez-Manoff's thesis, I'd recommend checking out this post at the Knight Science Journalism Tracker, which links to several critical stories and to Velasquez-Manoff's response to them. Read the rest

Antibiotic resistance: Watch a documentary tonight, join in a live chat tomorrow

Tonight at 10:00 Eastern/9:00 Central, PBS Frontline will air a documentary about the growing threat of antibiotic-resistant bacteria. I got a chance to see a preview of the show, and it's definitely interesting, including details I wasn't previously aware of, despite having written about this topic before. Particularly interesting: An emphasis on naturally occurring gene transfer between different species of bacteria, which is allowing antibiotic resistance to spread at an alarmingly quick rate. I had also not realized that antibiotic-resistant bacteria probably kill more Americans every year than AIDS — "probably", because nobody is required to actually track and report this stuff. Your local hospital could be in the midst of a serious outbreak of antibiotic-resistant bacteria and, unless they choose to voluntarily release that information, you might never know.

Whether or not you get a chance to watch the documentary tonight, we hope you'll join us here tomorrow for a live chat session with the producers and a doctor who specializes in treating patients with antibiotic-resistant infections. That starts at noon Eastern/11:00 central, and will be moderated by either me or Rob. We've got some questions we're looking forward to addressing with the panel, and we hope you'll bring in some great questions, too. The first half of the chat will focus on the documentary. The second half will be aimed more at a practical understanding of what you can actually do to protect yourself, your family, and your community. Read the rest

Gut microbes may control your brain

At The Verge, Carrie Arnold writes about a scientist who thinks that our intestinal bacteria could have an influence on mental health. It's not proven, but it's not a totally crazy idea, either, and there's some good evidence supporting the connection. The catch: Even if what's happening in your gut affects what is happening in your head, there might not be much we can do change the mental health outcomes. Read the rest

From the front lines in the fight against antibiotic-resistant bacteria

Bacteria are becoming resistant to one of the last classes of antibiotics available to treat them, writes Maryn McKenna at Nature. Carbapenem-resistant Enterobacteriaceae are a family of lung, blood, and bladder infections that can turn horribly deadly. Meanwhile, at Scientific American, Charles Q. Choi writes about other scientists looking for ways to turn bacteria against one another, unleashing predatory microbes that can destroy drug-resistant bacteria. Read the rest

Working with your microbiome to produce better-scented breath

Our great, collective, ongoing realization that wiping out all the bacteria in our bodies may not actually be a great idea marches on. At Scientific American, Deborah Franklin writes about chronic halitosis — the sort of bad breath that doesn't go away with a simple brushing — and scientists' efforts to cure it by encouraging the growth of some mouth bacteria, instead of pouring Listerine on everything and letting God sort it out. Read the rest

A beautiful bacterium

David Goodsell of the Scripps Research Institute made this lovely watercolor illustration of a cell of Mycoplasma mycoides. This bacterium is the cause of a deadly respiratory disease that affects cattle and other cud-chewing animals.

If you've ever read much about zoonoses — diseases that pass from animals to humans — then you know that the domestication of livestock played a huge role in introducing many diseases to people. Living in close proximity to the animals we ate provided ample opportunities for those animals' diseases to jump over to us. What's interesting about Mycoplasma mycoides is that it represents a disease of animals that seems to have its origins in domestication, as well.

In 2012, scientists found evidence that suggests domesticating livestock — a process that resulted in closer living conditions for the animals and in animals from one herd being moved to other herds they likely wouldn't have otherwise had contact with — helped Mycoplasma mycoides evolve and spread. Today, different species of Mycoplasma mycoides cause a range of diseases that can kill between 10 and 70 percent of the cows they infect.

Goodsell's illustration is an attempt to show all the different parts of the bacterial cell, in the shapes, sizes, locations, and concentrations that those parts take in the real world. If you go to his site, you can see a legend explaining what everything is. Read the rest

How animals pass disease to humans

Given the ongoing outbreak of H7N9 flu in China (and, now, also Taiwan), this is a good time to listen to a fascinating podcast discussion with David Quammen. Quammen recently published a FANTASTIC book, Spillover, about zoonoses — the diseases that humans contract from animals. This includes bird flus like H7N9. It also includes AIDS and a whole host of familiar viruses and bacteria. Bonus: Scary disease girl Maryn McKenna has a cameo in the podcast, discussing the way news media (in China and the US) are covering H7N9 and what you can do to better understand what's happening. Read the rest

We are all star stuff

How scientists study the fossils of ancient bacteria to find clues to a 2.6-million-year-old supernovae. Jennifer Ouellette explains how the the bacteria incorporated elements from an exploding star into their bodies, and how those elements can still be found today. Read the rest

A spaceship that tastes like Grape-Nuts

This morning, Marketplace Tech Report had a story on a new cellulose-based building material that could be made by genetically engineered bacteria — altered versions of the bacteria that naturally make stuff like kombucha. This tech sounds like it's got a long way to go from laboratory to the real world, but if they can perfect the process and make it large enough quantities, what you'd end up with a strong, inexpensive goop that could be used to build everything from medical dressings, to digital paper, to spaceships. Yes, you could theoretically use this stuff to make rocket casings, according to R. Malcolm Brown, Jr., a professor of cell biology at UT Austin. And if you can build a rocket from this stuff, you could also break the same material back down into an edible, high-fiber foodstuff. Read the rest

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