One magic mushroom trip can permanently make you more open

Taking psychedelic mushrooms just once can change your personality for the rest of your life, according to Katherine MacLean, a postdoctoral researcher at The Johns Hopkins University School of Medicine.

From LiveScience:

The results, published today (Sept. 29) in the Journal of Psychopharmacology, revealed that while other aspects of personality stayed the same, openness increased after a psilocybin experience. The effect was especially persistent for those who reported a "mystical" experience with their dose. These mystical experiences were marked by a sense of profound connectedness, along with feelings of joy, reverence and peace, MacLean said.