In Goldman Sachs's April 10 report, "The Genome Revolution," its analysts ponder the rise of biotech companies who believe they will develop "one-shot" cures for chronic illnesses; in a moment of rare public frankness, the report's authors ask, "Is curing patients a sustainable business model?" Read the rest

A large-scale, long-term double-blind study found that low testosterone levels were far, far lower than previously suspected, and showed that taking testosterone supplements didn't confer most of its reputed benefits -- no memory improvement and no physical vitality. Read the rest

Ben Goldacre (previously) led a team that created the FDAAA Trials Tracker, "A live informatics tool to monitor compliance with FDA requirements to report clinical trial results." Read the rest

The Sackler family is best known for the buildings adorned with their names thanks to their acts of philanthropy, which is either motivated by a public spirit, or by the desperate need for some reputation washing as the public becomes increasingly aware that the family fortune was built on the perfection of shady techniques for marketing addictive drugs, which reached its zenith when Perdue, the family pharma business, created the Oxy epidemic, by falsifying addictiveness research and aggressively recruiting doctors to hook their patients on their lethal products. Read the rest

Hospital chain Intermountain Healthcare is leading a industry consortium representing 450 hospitals in total in an initiative to manufacture their own generic drugs, either directly or through subcontractors. Read the rest

Daranide is a drug that was approved for treating glaucoma in 1958; the public domain drug's manufacture has shifted around for decades, sending its price soaring and plummeting from $0.50/dose to $1365, down to free, and now to $109,500, courtesy of Strongbridge Biopharma, new owners of Taro Pharmaceutical Industries, who started making the drug after Merck discontinued its production. Read the rest

Pharmadouchebro/Larval Trump Martin Shkreli was convicted of securities fraud in August and then sent to jail in September for putting a bounty on a lock of Hillary Clinton's hair. Read the rest

When Trump's Health and Human Services secretary Tom Price lost his job for chartering private jets to fly him all around America, it left a vacancy in Trump's cabinet of billionaire gators that he's been filling the DC swamp with. Read the rest

Purdue cynically created the American opiod epidemic through a combination of bribing medical professionals to overprescribe Oxycontin, publishing junk science, and aggressively lobbying regulators at every level to turn a blind eye to the destruction of the lives of millions of patient; while the company settled a record-setting criminal case, the name of the secretive family of billionaires who run Purdue and profited from the Oxy epidemic is best known for philanthropy, not profiteering: the Sackler family. Read the rest

In September, we learned that the pharma giant Allergan had sold key patents to the St Regis Mohawk band in upstate New York, in a bid to avoid a streamlined patent-challenge process called inter partes review (IPR). Read the rest

The FDA's Sept 6 warning letter to Epipen manufacturer Meridian (a division of Pfizer) condemns the company for knowingly shipping out defective products that led to the death of the customers who paid hyper-inflated prices for the devices, which Meridian manufactured for notorious pharma profiteers Mylan. Read the rest

Before being convicted of felony securities fraud, smirking cartoon villain pharma-douche-bro Martin Shkreli had to be tried in front of a jury and this presented a unique problem because everyone hates Martin Shkreli, and thus more than 100 jurors were dismissed from the pool during pre-trial questioning. Here are some of the statements that led to those dismissals. Read the rest

In The Network Structure of Opioid Distribution on a Darknet Cryptomarket, (Sci-Hub mirror), a paper presented today at the American Sociological Association meeting in Montreal, social scientists Scott W. Duxbury and Dana L. Haynie lay out their findings on using fake bad reviews to disrupt the darknet drug-trade. Read the rest

Amazon has a ton of listings for "fish antibiotics" whose reviews reveal that the people who buy them are self-medicating because they can't afford a doctor's visit because they are uninsured or can't afford their insurance's co-payment. Read the rest

It's been years since the major pharma companies agreed to participate in the Registry of All Trials, meaning that they'd end the practice of only reporting on trials whose outcomes they were pleased with, leaving about half of all trials unreported-on. Read the rest

Gabriella Corley is a 9 year old with Type I diabetes who's allergic to the insulin covered by her low-income parents' healthcare; to live, she must take Sanofi's proprietary Apidra brand insulin, which has increased in price by 1,123% since 1996, and which is only covered to 25% by her insurer's Pharmacy Benefit Manager, CVS. Read the rest