The Colorado River toad (Incilius alvarius) secretes a substance called 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT). People in a research study at Maastricht University in the Netherlands "found that inhaling dried-and-powdered toad secretions resulted in increased life satisfaction, better mindfulness, and a decrease in psychopathological symptoms for the duration of the four-week-long study," according to ScienceAlert.

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