From the official blurb:
While Ralph is animated, the miseries he endures in the short film are far from made up. As Spencer Susser, the director of Save Ralph, says, "It's so important that Ralph feels real because he represents countless real animals who suffer every day." Susser, known for his film Hesher, is among a slate of powerhouse celebrities and influencers who collaborated with Humane Society International on the making of Save Ralph. In addition to Waititi as Ralph and Gervais as the interviewer, the film has Zac Efron as Bobby, Olivia Munn as Marshmallow, Pom Klementieff as Cinnamon and Tricia Helfer as Cottonballs.
Producer Jeff Vespa (Voices of Parkland) teamed up with the Arch Model studio of puppet maker supreme Andy Gent (Isle of Dogs, The Grand Budapest Hotel) on the production. https://hsi.global/SaveRalph
You can learn more about the Save Ralph campaign from the Humane Society International website.