Ayelet Waldman is a novelist, non fiction author, and former federal public defender. Her latest book is called A Really Good Day: How Microdosing Made a Mega Difference in My Mood, My Marriage, and My Life. I interviewed her this morning.

Why did you start microdosing?

I started microdosing because I was profoundly and dangerously depressed. I have a mood disorder and for many, many years my medication worked great. I took it, I did what my doctor told me and everything was fine. But at some point my medication stopped working. I tried all sorts of different things. And nothing helped. I was getting worse and worse and more and more full of despair and more and more full of rage and more and more unstable and I became suicidal. I started doing things like googling the effects of maternal suicide on children and I was so terrified that I was going to do something to myself, that I was going to hurt myself, that I decided to do something drastic and something that some people might think is crazy -- I decided to try microdosing with L.S.D.

Did it work?

Oh absolutely. It worked for sure. It's sub-perceptual. In fact, if I told you right now, "Hey Mark, I slipped a microdose of LSD. in your coffee," you wouldn't even know the difference. The effect for me was instantaneous. My depression lifted right away. The book is called A Really Good Day because at the end of that very first day, I looked back and I thought, "that was a really good day." It wasn't like everything was perfect. Read the rest